Research and Clinical Studies

Research and Clinical Studies

Lyme neuroborreliosis in Children: a Prospective Study of Clinical Features, Prognosis , and Outcome

Lyme borreliosis: a European Perspective on Diagnosis and Clinical Management

Antibiotic Treatment of Animals Infected with Borrelia burgdorferi

Lyme Disease: Current State of Knowledge

Lyme Disease in Pregnancy: Case Report and Review of the Literature


Lyme Disease Serology in Amylotrophic lateral sclerosis (ALS

Editor’s Note: Since ceftriaxone has been reported to have profound neuroprotective effects (Nature 433: 73-77, 2005) and is often used to treat Lyme disease with neurological complications, clinical studies are now in progress to assess its efficacy in the treatment of ALS.

Antibiotic Treatment Duration and Long-term Outcomes of Patients with Early Lyme Disease from a Lyme Disease –Hyperendemic Area

Efficacy of Antibiotic Prophylaxis for the Prevention of Lyme Disease: an Updated systemic Review and Meta-Analysis

Neurological Manifestations of Lyme Disease

A Case Revealing the Natural History of Untreated Lyme Disease ( Although the data are not shown in the publication, the author confirms that the IgG Western blot was positive by the CDC criteria and showed the presence of 21,28,30,39,41,45,58,66, and 93 kDa bands. )

Long-term Lyme Disease Antibiotic Therapy Beliefs Among New England Residents

On-going and Completed NIH-supported Clinical Trials on Lyme Disease

Musculoskeletal Features of Lyme Disease: Understanding the Pathogenesis of Clinical Findings Helps Make Appropriate Therapeutic Choices

Biodiversity of Borrelia burgdorferi Strains in Tissues of Lyme Disease Patients

Lyme Borreliosis

The Amber Theory of Lyme Arthritis: Initial Description and Clinical

The Nervous System as Ectopic Germinal Center: CXCL13 and IgG in Lyme Neuroborreliosis

ACritical Analysis of Treatment Trials of Rhesus macaques Infected with Borrelia burgdorferi Reveals Important Flaws in Experimental Design

Spirochete Antigens Persist Near Cartilage after Murine Borreliosis

A Novel Human Autoantigen, Endothelial Growth Factor, is a Target of T and B Cell Responses in Patients with Lyme Disease

Lyme Disease-Human Granulocytic Anaplasmosis Co-Infection-Impact of Case Definition on Co-Infected Rates and Illness

Differentiation of Reinfection from Relapse in Recurrent Lyme Disease

Detection of Borrelia burgdorferi Nucleic Acids after Antibiotic Treatment does not Confirm Viability

Reductions in Human Lyme Disease Risk Due to the Effects of Oral Vaccination on Tick-to-Mouse and Mouse-to-Tick Transmission

Common Misconceptions about Lyme Disease

Nervous System Lyme Disease: Diagnosis and Treatment

Borrelia burgdorferi BbHtrA Degrades Host ECM Proteins and Stimulates Release of Inflammatory Cytokines in Vitro

Non-viable Borrelia burgdorferi Induce Inflammatory Mediators and Apoptosis in Human Oligodendrocytes

A Systematic Review of Borrelia burgdorferi Morphologic Variants does not Support a Role in Chronic Lyme Disease

Evidence for Strain-specific Immunity in Patients Treated for Early Lyme Disease

Functional Outcomes in Patients with Borrelia burgdorferi Reinfection

Xenodiagnsosis to Detect Borrelia burgdorferi Infection: a First-in-human Study —

The Role of Eocosanoids in Experimental Lyme Arthritis

Oral Doxycycline for Lyme Neuroborreliosis with Symptoms of Encephalitis,, myelitis, Vasculitis, or Intracranial Hypertension

Death From Inappropriate Therapy for Lyme Disease

Natural Killer Cell Counts are not Different Between Patients with Post-Lyme Disease Syndrome and Controls

Implications of Gender in Chronic Lyme Disease

Death Due to Community-associated Clostridium difficile in a Woman Receiving Prolonged Antibiotic Therapy for Lyme Disease

Ceftriaxone-induced Hemolysis in a Child with Lyme Arthritis: a case for Antimicrobial Stewardship

Sympathetic Neural Hyperalgesia Edema Syndrome, a Frequent Cause of Pelvic Pain in Women, Mistaken for Lyme Disease with Chronic Fatigue

A Systematic Review of Borrelia burgdorferi Morphologic Variants does not Support a Role in Chronic Lyme Disease

Views and Facts About Chronic Lyme Disease from the National Institute of Allergy and Infectious Diseases (NIAID)